TY - JOUR AU - Khaiwal Ravindra AU - Sreekanth Vakacherla AU - Tanbir Singh AU - Adithi Upadhya AU - Preety Rattan AU - Suman Mor AB - PM2.5 is one of the major contributors to air pollution in India, resulting in poor air quality and human health issues. The current study explores the applicability of TTAinterfaceTrendAnalysis (an ‘R’ language-based Graphical User Interface package) in estimating the annual and month-wise trends in PM2.5 over five Indian megacities (New Delhi, Kolkata, Mumbai, Hyderabad, and Chennai). The package offers a one-stop solution for various statistical analyses such as data imputation, outlier detection, trend analysis, data smoothing, diagnostic tests, etc. The trends are estimated using seven (2014–2020) years of PM2.5 data. All estimated month-wise trends of PM2.5 over the study cities were found to be statistically non-significant. Annual trends (both with and without applying data smoothing techniques) were found to be statistically significant with magnitudes ranging between − 0.27 and − 5.2 µg m−3 y−1 (negative sign indicates a declining trend). Autocorrelation analysis and normality tests are also conducted using the inbuilt options of TTAinterfaceTrendAnalysis. Results obtained are thoroughly discussed and compared with those of similar contemporary studies. To our knowledge, the current study is the first to apply TTAinterfaceTrendAnalysis for quantifying long-term trends in PM2.5. The sensitivity of the trend estimates due to the inclusion of COVID-19 lockdown PM2.5 data was also examined. The net impact of lockdown on the PM2.5 long-term trend ranged between − 0.13 and 2.29 µg m−3 y−1 across the study cities. M3 - Original Paper N2 - PM2.5 is one of the major contributors to air pollution in India, resulting in poor air quality and human health issues. The current study explores the applicability of TTAinterfaceTrendAnalysis (an ‘R’ language-based Graphical User Interface package) in estimating the annual and month-wise trends in PM2.5 over five Indian megacities (New Delhi, Kolkata, Mumbai, Hyderabad, and Chennai). The package offers a one-stop solution for various statistical analyses such as data imputation, outlier detection, trend analysis, data smoothing, diagnostic tests, etc. The trends are estimated using seven (2014–2020) years of PM2.5 data. All estimated month-wise trends of PM2.5 over the study cities were found to be statistically non-significant. Annual trends (both with and without applying data smoothing techniques) were found to be statistically significant with magnitudes ranging between − 0.27 and − 5.2 µg m−3 y−1 (negative sign indicates a declining trend). Autocorrelation analysis and normality tests are also conducted using the inbuilt options of TTAinterfaceTrendAnalysis. Results obtained are thoroughly discussed and compared with those of similar contemporary studies. To our knowledge, the current study is the first to apply TTAinterfaceTrendAnalysis for quantifying long-term trends in PM2.5. The sensitivity of the trend estimates due to the inclusion of COVID-19 lockdown PM2.5 data was also examined. The net impact of lockdown on the PM2.5 long-term trend ranged between − 0.13 and 2.29 µg m−3 y−1 across the study cities. PY - 2023 SN - 1436-3259 T2 - Stochastic Environmental Research and Risk Assessment TI - Long-term trend of PM2.5 over five Indian megacities using a new statistical approach UR - https://link.springer.com/article/10.1007/s00477-023-02595-x#Ack1 ER -